Influenza Virus Partially Counteracts Restriction Imposed by Tetherin/BST-2

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Influenza virus partially counteracts restriction imposed by tetherin/BST-2.

Influenza virus infections lead to a burst of type I interferon (IFN) in the human respiratory tract, which most probably accounts for a rapid control of the virus. Although in mice, IFN-induced Mx1 factor mediates a major part of this response, the situation is less clear in humans. Interestingly, a recently identified IFN-induced cellular protein, tetherin (also known as CD317, BST-2, or HM1....

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Influenza Virus Partially Counteracts a Restriction Imposed by Tetherin/BST-2

Department of Dermatology and Wound Healing, Institute of Infection and Immunity, Cardiff University School of Medicine, Cardiff, Wales, United Kingdom. Dept. of Microbiology and Molecular Medicine, University of Geneva, Switzerland. Laboratory of Virology, Swiss National Reference Centre of Influenza, Division of Infectious Diseases, University Hospitals and Medical School of Geneva, Universit...

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ژورنال

عنوان ژورنال: Journal of Biological Chemistry

سال: 2012

ISSN: 0021-9258

DOI: 10.1074/jbc.m111.319996